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Crockpot Spicy Queso Roast Beef

Published: Jun 21, 2026 by Terri Weir · Leave a Comment · This post may contain affiliate links

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If you’re looking for an easy dinner recipe packed with bold flavor, this crockpot spicy queso roast beef is exactly what you need. Tender beef roast slow-cooks for hours in a rich mixture of spicy jalapeño queso, salsa verde, onions, jalapenos, and seasonings until it’s fall-apart tender and loaded with flavor.

Two what plates with blue trim with crockpot spicy queso roast beef on them, and a title overlay at the top.

This zesty, cheesy roast beef is super tender and perfect for any weeknight meal, served with sides like loaded mashed potatoes or stuffed into my homemade flour tortillas for a delicious twist on beef enchiladas.

For more easy, Mexican-inspired meals, try my sausage breakfast enchiladas, fried shrimp tacos, and Mexican street corn pasta salad.

Jump to:
  • Why You’ll Love This Recipe
  • Key Ingredients
  • Variations
  • How to Make Crockpot Spicy Queso Roast Beef
  • Expert Tips
  • Crockpot Spicy Queso Roast Beef FAQs
  • Tasty Sides for Your Queso Beef
  • Crockpot Spicy Queso Roast Beef

Why You’ll Love This Recipe

  • Super easy dump-and-go slow cooker recipe
  • Rich, creamy queso flavor in every bite
  • Perfectly tender shredded beef
  • Great for tacos, burritos, sandwiches, enchiladas, and rice bowls
  • Excellent for meal prepping
  • Makes enough to feed a crowd

Key Ingredients

You’ll find a full list of ingredients and their exact amounts in the recipe card at the bottom of the post.

A wood surface with all the ingredients placed o it to make crockpot spicy queso roast beef.
  • Beef Eye of Round Roast: Slow cooking transforms this lean cut into tender, flavorful shredded beef that’s perfect for soaking up all the other flavors.
  • Spicy Jalapeno Queso: Adds a rich, creamy texture and cheesy flavor while helping keep the beef moist during the long cooking process.
  • Salsa Verde: Adds bright, tangy flavor that cuts through the richness of the queso and beef.
  • Slap Ya Mama, Garlic Salt & Red Pepper Flakes: A simple blend that builds layers of flavor with just enough spice to make the dish pop without overpowering it.

Variations

  • Mild: Use regular queso and leave out the jalapenos.
  • Chuck Roast: Chuck roast works wonderfully in place of eye of round.
  • Queso Pork: Make a crock pot boneless pork loin version.
  • Queso Brisket: Simmer the queso mixture on the stovetop and add shredded leftover baked brisket.
  • Queso Chicken: Mix shredded rotisserie chicken into the queso mixture.

How to Make Crockpot Spicy Queso Roast Beef

A black crock pot with diced onions and jalapenos, and a whole round roast placed in it.

Step 1: Add the diced onions and jalapenos to the slow cooker. Then, add the eye of round.

A black crockpot with diced onions, jalapenos, a round roast, and seasonings on top of the roast.

Step 2: Top the beef with the seasonings, jalapeno queso, and salsa verde.

A black crockpot with round roast covered with seasonings, queso, and salsa verde before being slow cooked.

Step 3: Cover and cook on high or low until the beef shreds easily with a fork.

A white plate with blue trim with a slow cooked round roast on it.

Step 4: Enjoy!

Expert Tips

  • If you use a chuck roast, trim away the large hunks of fat that it sometimes has. It makes the filling greasy.
  • Allow the shredded beef to sit in the sauce for a few minutes before serving to let it absorb even more flavor.
  • Spray the slow cooker with non-stick spray for easy cleanup.
  • You can cook the roast on high or low, but low yields the most tender results.
  • Cool the roast a bit before slicing.
  • If you choose to shred the roast, do so as soon as you can safely handle it for the easiest shredding.

Crockpot Spicy Queso Roast Beef FAQs

What cut of beef is best for crockpot roast beef?

Eye of round roast works great for this recipe, but chuck roast is another excellent option. Chuck roast has more marbling, which creates an even more tender and flavorful shredded beef.

Can I make crockpot spicy queso roast beef ahead of time?

Yes, you can. In fact, it’s perfect for meal prep because the flavors continue to develop as it sits.

What can I serve with queso roast beef?

This roast beef works well with sides like Spanish rice, Mexican rice, beans, guac or salsa with chips, and most of your other Mexican and Tex-Mex favorites.

How can I use queso roast beef?

Use this roast beef in dishes like tacos, burritos, quesadillas, nachos, enchiladas, rice bowls, sandwiches, lettuce wraps, or loaded baked potatoes.

How long does crockpot spicy queso roast beef last?

You can refrigerate it for up to 4 days. For longer storage, freeze it for up to 3 months in a freezer-safe container.

A round white plate with blue trim with a slice of slow cooked roast beef that has been cut into bite-size pieces with another plate in the background.

Tasty Sides for Your Queso Beef

  • A red and black plaid plate with mashed potatoes, corn and green beans on it.
    Fluffy Mashed Potatoes
  • Homemade Spanish Rice
  • Instant Pot White Rice
  • Creamy Jalapeno Cilantro Salsa

If you try this recipe and love it, please be sure to leave a 5 ★★★★★ rating below and leave a comment! You can also pin it to your favorite Pinterest boards and save it for later.

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Two what plates with blue trim with crockpot spicy queso roast beef on them, and a title overlay at the top.

Crockpot Spicy Queso Roast Beef

Great Grub, Delicious Treats
Crockpot spicy queso roast beef is cooked for hours in a blend of jalapeno queso, salsa verde, onions, and seasonings, until super tender.
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Prep Time 15 minutes mins
Cook Time 6 hours hrs
Total Time 6 hours hrs 15 minutes mins
Course Dinner, Lunch
Cuisine American, Mexican
Servings 8 Servings
Calories 375 kcal

Ingredients
  

  • 2 ½ pounds beef eye of round roast
  • 1 large onion, diced
  • 1 jalapeno, diced
  • 1 teaspoon Slap Ya Mama seasoning
  • 1 teaspoon black pepper
  • 1 teaspoon garlic salt
  • ½ teaspoon red pepper flakes
  • 15.25 ounce spicy jalapeno queso, we used On The Border brand
  • 12 ounce salsa verde
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Instructions
 

  • Spray a 6 or 8 quart crockpot with non-stick cooking spray.
  • Add diced onions and diced jalapenos to the bottom of the pot.
  • Add the beef roast on top of the onions and sprinkle with all of the seasonings.
  • Pour the queso over the beef and then pour the salsa verde over the top.
  • Cover and cook on high for 6 hours or low for 10-12 hours.

Notes

Tips
  • If you use a chuck roast, trim away the large hunks of fat that it sometimes has. It makes the filling greasy.
  • Allow the shredded beef to sit in the sauce for a few minutes before serving to let it absorb even more flavor.
  • Spray the slow cooker with non-stick spray for easy cleanup.
  • You can cook the roast on high or low, but low yields the most tender results.
  • Cool the roast a bit before slicing.
  • If you choose to shred the roast, do so as soon as you can safely handle it for the easiest shredding.
 
Nutritional values are approximate.
 
Please note that these values can change with different brands and any modifications made to the recipe. For the most accurate information, use a nutritional calculator with the exact brands and measurements.

Nutrition

Calories: 375kcalCarbohydrates: 9gProtein: 38gFat: 19gSaturated Fat: 10gMonounsaturated Fat: 3gCholesterol: 128mgSodium: 1564mgPotassium: 735mgFiber: 1gSugar: 7gVitamin A: 797IUVitamin C: 5mgCalcium: 227mgIron: 3mg
Keyword crockpot roast beef, crockpot spicy queso roast beef, queso roast beef, slow cooker queso roast beef, slow cooker roast beef, spicy roast beef
Tried this recipe?Let us know how it was!
A two panel image collage of slow cooked spicy queso roast beef on white plates with blue trim, and a title overlay in the center.
A three panel image collage of crockpot spicy queso roast beef, and a title overlay at the top.
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Welcome to Great Grub, Delicious Treats! Hello, my name is Terri and I'm so glad you stopped by. I'm a self taught cook/foodie at heart, mom to three kids, photographer and have a love for amazing food. I left my full time job of being a hospice admissions RN, which was super tough and extremely sad, and at times, very rewarding to be there for the patients and families to blog full time which I absolutely love. I hope you enjoy, and check out, all of the delicious recipes on my site while you're here! And don't forget to sign up to receive every new recipe right to your email. Thanks again for stopping by! :)

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Welcome to Great Grub, Delicious Treats! Hello, my name is Terri and I'm so glad you stopped by. I'm a self taught cook/foodie at heart, mom to three kids, photographer and have a love for amazing food. I left my full time job of being a hospice admissions RN, which was super tough and extremely sad, and at times, very rewarding to be there for the patients and families to blog full time which I absolutely love. I hope you enjoy, and check out, all of the delicious recipes on my site while you're here! And don't forget to sign up to receive every new recipe right to your email. Thanks again for stopping by! :) Read More…

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